Acromegaly or pituitary gigantism (Q39840): Difference between revisions
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Acromegalia é um distúrbio adquirido relacionado à produção excessiva de hormônio do crescimento (GH) e caracterizado por desfiguração somática progressiva (envolvendo principalmente a face e extremidades) e manifestações sistêmicas. As principais características clínicas são extremidades alargadas (mãos e pés), dedos grossos, alargados e atarracados e tecido mole espessado. A doença também tem consequências reumatológicas, cardiovasculares, respiratórias e metabólicas que determinam o seu prognóstico. Na maioria dos casos, a acromegalia está relacionada a um adenoma hipofisário, puramente secretor de GH (60%) ou misto. A cirurgia transesfenoidal costuma ser o tratamento de primeira linha. Quando a cirurgia não corrige a hipersecreção de GH/IGF-I, o tratamento com análogos da somatostatina e/ou radioterapia pode ser usado. | |||||||||||||||
| description / en | description / en | ||||||||||||||
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterised by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory and metabolic consequences which determine its prognosis. In the majority of cases, acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or radiotherapy can be used. | |||||||||||||||
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| Property / Canonical URI: https://id.who.int/icd/entity/825410563 / rank | |||||||||||||||
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CID11:5A60.0 | |||||||||||||||
| Property / CURIE: CID11:5A60.0 / rank | |||||||||||||||
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dki-india-5A60.0 | |||||||||||||||
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| Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank | |||||||||||||||
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13 August 2026
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| Property / Collection date: 13 August 2026 / rank | |||||||||||||||
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| Property / Linked ICD 10: E22.0 / rank | |||||||||||||||
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Latest revision as of 05:23, 13 August 2026
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterised by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory and metabolic consequences which determine its prognosis. In the majority of cases, acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or radiotherapy can be used.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5A60.0 |
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| English | Acromegaly or pituitary gigantism |
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterised by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The main clinical features are broadened extremities (hands and feet), widened thickened and stubby fingers, and thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory and metabolic consequences which determine its prognosis. In the majority of cases, acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or radiotherapy can be used. |
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CID11:5A60.0
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dki-india-5A60.0
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Concluído
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13 August 2026
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