Frasier syndrome (Q108407): Difference between revisions

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Síndrome de Frasier é caracterizada pela associação de distúrbio do desenvolvimento sexual (DDS) 46, XY e nefropatia glomerular, com alto risco de desenvolvimento de gonadoblastoma. Pacientes com síndrome de Frasier apresentam genitália externa feminina normal e gônadas estriadas e têm cariótipo 46, XY. A nefropatia se apresenta durante a infância com proteinúria e síndrome nefrótica, e progride para doença renal em estágio terminal na adolescência ou na idade adulta.
description / endescription / en
 
Frasier syndrome is characterised by the association of 46,XY disorder of sex development (DSD) and glomerular nephropathy, with a high risk of developing gonadoblastoma. Patients with Frasier syndrome present with normal female external genitalia and streak gonads, and have a 46,XY karyotype. Nephropathy presents during childhood with proteinuria and nephrotic syndrome, and progresses to end-stage renal disease in adolescence or adulthood.
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Property / Canonical URI: https://id.who.int/icd/entity/1659542949 / rank
 
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CID11:ID_1659542949
Property / CURIE: CID11:ID_1659542949 / rank
 
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dki-india-ID_1659542949
Property / Canary Token: dki-india-ID_1659542949 / rank
 
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Concluído
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Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank
 
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16 August 2026
Timestamp+2026-08-16T00:00:00Z
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CalendarGregorian
Precision1 day
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Property / Collection date: 16 August 2026 / rank
 
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Latest revision as of 15:28, 17 August 2026

Frasier syndrome is characterised by the association of 46,XY disorder of sex development (DSD) and glomerular nephropathy, with a high risk of developing gonadoblastoma. Patients with Frasier syndrome present with normal female external genitalia and streak gonads, and have a 46,XY karyotype. Nephropathy presents during childhood with proteinuria and nephrotic syndrome, and progresses to end-stage renal disease in adolescence or adulthood.
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    Frasier syndrome
    Frasier syndrome is characterised by the association of 46,XY disorder of sex development (DSD) and glomerular nephropathy, with a high risk of developing gonadoblastoma. Patients with Frasier syndrome present with normal female external genitalia and streak gonads, and have a 46,XY karyotype. Nephropathy presents during childhood with proteinuria and nephrotic syndrome, and progresses to end-stage renal disease in adolescence or adulthood.

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      CID11:ID_1659542949
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      dki-india-ID_1659542949
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      Concluído
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      16 August 2026
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