Obesity due to melanocortin-4 receptor deficiency (Q106802): Difference between revisions

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Latest revision as of 13:48, 17 August 2026

Melanocortin 4 receptor (MC4R) deficiency is the commonest form of monogenic obesity identified so far, and is characterised by severe obesity, an increase in lean body mass and bone mineral density, increased linear growth in early childhood, hyperphagia beginning in the first year of life and severe hyperinsulinaemia, in the presence of preserved reproductive function.

Language	Label	Description	Also known as
default for all languages	ID_132077929
English	Obesity due to melanocortin-4 receptor deficiency	Melanocortin 4 receptor (MC4R) deficiency is the commonest form of monogenic obesity identified so far, and is characterised by severe obesity, an increase in lean body mass and bone mineral density, increased linear growth in early childhood, hyperphagia beginning in the first year of life and severe hyperinsulinaemia, in the presence of preserved reproductive function.