Necrotising polymyositis (Q90737): Difference between revisions

@@ description / pt-br / description / pt-br @@
+Polimiosite necrosante é um transtorno muscular inflamatório, imune caracterizado por níveis elevados de CK, fraqueza muscular moderada a grave de início agudo ou subagudo, e com características histológicas de necrose da fibra muscular mediada por macrófagos como principal célula efetora. Não há infiltrados de células T ou expressão de MHC-I. No entanto, alguns pacientes têm anticorpos contra partículas de reconhecimento de sinal (SRP). A doença é multifatorial: câncer, infecção viral, uso de estatinas, exposição a agentes tóxicos ou processo autoimune subjacente; outros não têm outra doença ou exposição aparente a agentes exógenos.
@@ description / en / description / en @@
+Necrotising polymyositis is an immune inflammatory muscle disorders characterised by high CK level, moderate to severe muscle weakness of acute or subacute onset and with histological features of muscle fibre necrosis mediated by macrophages as the main effector cell. There are no T cell infiltrates or MHC-I expression. However, some patients have antibodies against signal recognition particles (SRP). The disease is multifactorial: cancer, viral infection, use of statins, exposure to toxic agents, or underlying autoimmune process; others have no other disease or apparent exposure to exogenous agents.
@@ Property / Canonical URI @@
+https://id.who.int/icd/entity/194675725
@@ Property / Canonical URI: https://id.who.int/icd/entity/194675725 / rank @@
+Normal rank
@@ Property / CURIE @@
+CID11:ID_194675725
@@ Property / CURIE: CID11:ID_194675725 / rank @@
+Normal rank
@@ Property / Canary Token @@
+dki-india-ID_194675725
@@ Property / Canary Token: dki-india-ID_194675725 / rank @@
+Normal rank
@@ Property / Verification Status @@
+Concluído
@@ Property / Verification Status: Concluído / rank @@
+Normal rank
@@ Property / Knowledge Architect @@
+https://pauloleads.com.br/cases-publicos/
+Normal rank
@@ Property / Collection date @@
+August 2026Timestamp +2026-08-13T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
-Timestamp
++2026-08-13T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / Collection date: 13 August 2026 / rank @@
+Normal rank

Latest revision as of 17:43, 15 August 2026

Necrotising polymyositis is an immune inflammatory muscle disorders characterised by high CK level, moderate to severe muscle weakness of acute or subacute onset and with histological features of muscle fibre necrosis mediated by macrophages as the main effector cell. There are no T cell infiltrates or MHC-I expression. However, some patients have antibodies against signal recognition particles (SRP). The disease is multifactorial: cancer, viral infection, use of statins, exposure to toxic agents, or underlying autoimmune process; others have no other disease or apparent exposure to exogenous agents.

Language	Label	Description	Also known as
default for all languages	ID_194675725
English	Necrotising polymyositis	Necrotising polymyositis is an immune inflammatory muscle disorders characterised by high CK level, moderate to severe muscle weakness of acute or subacute onset and with histological features of muscle fibre necrosis mediated by macrophages as the main effector cell. There are no T cell infiltrates or MHC-I expression. However, some patients have antibodies against signal recognition particles (SRP). The disease is multifactorial: cancer, viral infection, use of statins, exposure to toxic agents, or underlying autoimmune process; others have no other disease or apparent exposure to exogenous agents.