Autoimmune hyperexcitability syndrome with continuous muscle fibre activity or Morvan syndrome (Q84060): Difference between revisions
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CID11:ID_1155795500 | |||||||||||||||
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13 August 2026
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Latest revision as of 09:25, 15 August 2026
The autoimmune hyperexcitability syndrome with continuous muscle fibre activity (CMFA), is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is often antibody mediated in particular with potassium channel antibodies (VGKC) and anti-CASPR2. It responds to symptomatic therapy and immune therapies.
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| default for all languages | ID_1155795500 |
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| English | Autoimmune hyperexcitability syndrome with continuous muscle fibre activity or Morvan syndrome |
The autoimmune hyperexcitability syndrome with continuous muscle fibre activity (CMFA), is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is often antibody mediated in particular with potassium channel antibodies (VGKC) and anti-CASPR2. It responds to symptomatic therapy and immune therapies. |
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CID11:ID_1155795500
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dki-india-ID_1155795500
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Concluído
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13 August 2026
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