Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis (Q43591): Difference between revisions

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Latest revision as of 10:40, 13 August 2026

This is an acute hepatocellular injury that develops within 1 to 20 weeks after starting treatment. The histological lesions consist mainly of focal, zonal or bridging necrosis, but lobular and portal tract inflammation evident with drug hepatitis. Extrahepatic features of drug hypersensitivity, including rash, lymphadenopathy, eosinophilia or other systemic features, are observed in some cases.

Language	Label	Description	Also known as
default for all languages	DB95.0
English	Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis	This is an acute hepatocellular injury that develops within 1 to 20 weeks after starting treatment. The histological lesions consist mainly of focal, zonal or bridging necrosis, but lobular and portal tract inflammation evident with drug hepatitis. Extrahepatic features of drug hypersensitivity, including rash, lymphadenopathy, eosinophilia or other systemic features, are observed in some cases.