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	<id>https://determinar.ia.br/w/index.php?action=history&amp;feed=atom&amp;title=Item%3AQ52672</id>
	<title>Item:Q52672 - Revision history</title>
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	<updated>2026-10-11T14:42:25Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.45.4</generator>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229786&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-13T23:58:59Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P78&quot; href=&quot;/wiki/Property:P78&quot;&gt;Knowledge Architect&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://pauloleads.com.br/cases-publicos/&quot;&gt;https://pauloleads.com.br/cases-publicos/&lt;/a&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P78&quot; href=&quot;/wiki/Property:P78&quot;&gt;Knowledge Architect&lt;/a&gt;: &lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://pauloleads.com.br/cases-publicos/&quot;&gt;https://pauloleads.com.br/cases-publicos/&lt;/a&gt; / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229787&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-13T23:58:59Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P80&quot; href=&quot;/wiki/Property:P80&quot;&gt;Collection date&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;b class=&quot;wb-details wb-time-details wb-time-rendered&quot;&gt;13 August 2026&lt;/b&gt;&lt;table class=&quot;wb-details wb-time-details&quot;&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-isotime&quot;&gt;Timestamp&lt;/th&gt;&lt;td class=&quot;wb-time-isotime&quot;&gt;+2026-08-13T00:00:00Z&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-timezone&quot;&gt;Timezone&lt;/th&gt;&lt;td class=&quot;wb-time-timezone&quot;&gt;+00:00&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-calendar&quot;&gt;Calendar&lt;/th&gt;&lt;td class=&quot;wb-time-calendar&quot;&gt;Gregorian&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-precision&quot;&gt;Precision&lt;/th&gt;&lt;td class=&quot;wb-time-precision&quot;&gt;1 day&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-before&quot;&gt;Before&lt;/th&gt;&lt;td class=&quot;wb-time-before&quot;&gt;0&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-after&quot;&gt;After&lt;/th&gt;&lt;td class=&quot;wb-time-after&quot;&gt;0&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P80&quot; href=&quot;/wiki/Property:P80&quot;&gt;Collection date&lt;/a&gt;: 13 August 2026 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229783&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
		<link rel="alternate" type="text/html" href="https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229783&amp;oldid=prev"/>
		<updated>2026-08-13T23:58:58Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P67&quot; href=&quot;/wiki/Property:P67&quot;&gt;CURIE&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;CID11:ID_398872780&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P67&quot; href=&quot;/wiki/Property:P67&quot;&gt;CURIE&lt;/a&gt;: CID11:ID_398872780 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229784&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
		<link rel="alternate" type="text/html" href="https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229784&amp;oldid=prev"/>
		<updated>2026-08-13T23:58:58Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P70&quot; href=&quot;/wiki/Property:P70&quot;&gt;Canary Token&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;dki-india-ID_398872780&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P70&quot; href=&quot;/wiki/Property:P70&quot;&gt;Canary Token&lt;/a&gt;: dki-india-ID_398872780 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229785&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
		<link rel="alternate" type="text/html" href="https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229785&amp;oldid=prev"/>
		<updated>2026-08-13T23:58:58Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P86&quot; href=&quot;/wiki/Property:P86&quot;&gt;Verification Status&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Concluído&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P86&quot; href=&quot;/wiki/Property:P86&quot;&gt;Verification Status&lt;/a&gt;: Concluído / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229781&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update-languages-short:0||pt-br, en */</title>
		<link rel="alternate" type="text/html" href="https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;diff=229781&amp;oldid=prev"/>
		<updated>2026-08-13T23:58:57Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed label, description and/or aliases in pt-br, en&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / pt-br&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / pt-br&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;A doença de Niemann-Pick é um distúrbio de armazenamento lisossomal autossômico recessivo causado pela atividade deficiente da esfingomielinase ácida, abrangendo duas formas clinicamente distintas: tipo A e tipo B. O tipo A é caracterizado por um início precoce, no primeiro ano de vida, distúrbios digestivos, atraso de crescimento, hepatoesplenomegalia grave e sintomas neurológicos graves (retardo psicomotor, hipotonia). Os transtornos neurológicos graves e as infecções pulmonares levam à morte precoce, geralmente por volta dos 4 anos de idade. No tipo B, o início ocorre em qualquer idade (até a idade adulta) e o sinal mais constante é a hepatoesplenomegalia, que pode estar associada a sintomas pulmonares.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / en&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / en&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Niemann-Pick disease is an autosomal recessive lysosomal storage disorder caused by the deficient activity of acid sphingomyelinase, encompassing two clinically distinct forms: type A and type B. Type A is characterised by an early onset, within the first year of life, digestive disorders, failure to thrive, major hepatosplenomegaly, and severe neurologic symptoms (psychomotor retardation, hypotonia). The severe neurological disorders and pulmonary infections lead to an early death, often around the age of 4. In type B ), onset occurs at any age (until adulthood) and the most constant sign is hepatosplenomegaly, which can be associated with pulmonary symptoms.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
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		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-13T23:58:57Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:58, 13 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P68&quot; href=&quot;/wiki/Property:P68&quot;&gt;Canonical URI&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://id.who.int/icd/entity/398872780&quot;&gt;https://id.who.int/icd/entity/398872780&lt;/a&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P68&quot; href=&quot;/wiki/Property:P68&quot;&gt;Canonical URI&lt;/a&gt;: &lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://id.who.int/icd/entity/398872780&quot;&gt;https://id.who.int/icd/entity/398872780&lt;/a&gt; / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
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		<updated>2026-08-13T23:58:56Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Created a new Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;a href=&quot;https://determinar.ia.br/w/index.php?title=Item:Q52672&amp;amp;diff=229780&quot;&gt;Show changes&lt;/a&gt;</summary>
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