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	<id>https://determinar.ia.br/w/index.php?action=history&amp;feed=atom&amp;title=Item%3AQ104865</id>
	<title>Item:Q104865 - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://determinar.ia.br/w/index.php?action=history&amp;feed=atom&amp;title=Item%3AQ104865"/>
	<link rel="alternate" type="text/html" href="https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;action=history"/>
	<updated>2026-10-03T07:41:51Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.45.4</generator>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605065&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-17T10:43:35Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P78&quot; href=&quot;/wiki/Property:P78&quot;&gt;Knowledge Architect&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://pauloleads.com.br/cases-publicos/&quot;&gt;https://pauloleads.com.br/cases-publicos/&lt;/a&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P78&quot; href=&quot;/wiki/Property:P78&quot;&gt;Knowledge Architect&lt;/a&gt;: &lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://pauloleads.com.br/cases-publicos/&quot;&gt;https://pauloleads.com.br/cases-publicos/&lt;/a&gt; / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605066&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-17T10:43:35Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P80&quot; href=&quot;/wiki/Property:P80&quot;&gt;Collection date&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;b class=&quot;wb-details wb-time-details wb-time-rendered&quot;&gt;16 August 2026&lt;/b&gt;&lt;table class=&quot;wb-details wb-time-details&quot;&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-isotime&quot;&gt;Timestamp&lt;/th&gt;&lt;td class=&quot;wb-time-isotime&quot;&gt;+2026-08-16T00:00:00Z&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-timezone&quot;&gt;Timezone&lt;/th&gt;&lt;td class=&quot;wb-time-timezone&quot;&gt;+00:00&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-calendar&quot;&gt;Calendar&lt;/th&gt;&lt;td class=&quot;wb-time-calendar&quot;&gt;Gregorian&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-precision&quot;&gt;Precision&lt;/th&gt;&lt;td class=&quot;wb-time-precision&quot;&gt;1 day&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-before&quot;&gt;Before&lt;/th&gt;&lt;td class=&quot;wb-time-before&quot;&gt;0&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;th class=&quot;wb-time-after&quot;&gt;After&lt;/th&gt;&lt;td class=&quot;wb-time-after&quot;&gt;0&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P80&quot; href=&quot;/wiki/Property:P80&quot;&gt;Collection date&lt;/a&gt;: 16 August 2026 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;!-- diff cache key my_wiki:diff:1.41:old-605065:rev-605066:lang-en --&gt;
&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605062&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-17T10:43:34Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P67&quot; href=&quot;/wiki/Property:P67&quot;&gt;CURIE&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;CID11:ID_1394279590&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P67&quot; href=&quot;/wiki/Property:P67&quot;&gt;CURIE&lt;/a&gt;: CID11:ID_1394279590 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
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		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605063&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-17T10:43:34Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P70&quot; href=&quot;/wiki/Property:P70&quot;&gt;Canary Token&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;dki-india-ID_1394279590&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P70&quot; href=&quot;/wiki/Property:P70&quot;&gt;Canary Token&lt;/a&gt;: dki-india-ID_1394279590 / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605064&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update:0| */</title>
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		<updated>2026-08-17T10:43:34Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed an Item&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P86&quot; href=&quot;/wiki/Property:P86&quot;&gt;Verification Status&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Concluído&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P86&quot; href=&quot;/wiki/Property:P86&quot;&gt;Verification Status&lt;/a&gt;: Concluído / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
	</entry>
	<entry>
		<id>https://determinar.ia.br/w/index.php?title=Item:Q104865&amp;diff=605060&amp;oldid=prev</id>
		<title>Determinaradmin: /* wbeditentity-update-languages-short:0||pt-br, en */</title>
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		<updated>2026-08-17T10:43:33Z</updated>

		<summary type="html">&lt;p&gt;‎&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;Changed label, description and/or aliases in pt-br, en&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / pt-br&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / pt-br&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Deficiência de acetilcolinesterase (AChE) da placa motora autossômica recessiva, um subtipo de síndrome miastênica congênita (SMC) causada por mutações do peptídeo da cauda colagênia da acetilcolinesterase (ColQ) com início do nascimento até 2 anos, apresenta-se com hipotonia e fraqueza muscular proximal e/ou com marcos motores atrasados. Fraqueza muscular extraocular e ptose estão sempre presentes, sintomas bulbar em metade dos pacientes, crises respiratórias em um terço. Reflexo pupilar à luz ocasionalmente está lentificado. O curso varia de fraqueza grave e progressiva no neonato a sintomas menos graves durante a infância com progressão mínima. Mais de 80% deambula durante seguimento e não apresenta problemas respiratórios, à despeito de poderem apresentar crises. Os pacientes respondem à efedrina e salbutamol e não aos inibidores da AChE.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / en&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;description / en&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Autosomal recessive endplate Acetylcholinesterase (AChE) deficiency, a Congenital myasthenic syndrome (CMS) subtype caused by Collagenic tail of endplate acetylcholinesterase (ColQ) mutations with onset from birth to 2 years, presents with hypotonia and proximal muscle weakness or delayed motor milestones. Extraocular muscle weakness and ptosis are always present, bulbar symptoms in half of the patients, respiratory crises in one-third. Occasionally delayed pupillary light reflex. The course varies from progressive severe weakness in the neonate to less severe symptoms during childhood with minimal progression. More than 80% is ambulant on follow-up and has no respiratory trouble despite crises. The patients respond to ephedrine and salbutamol, not to AChE inhibitors.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
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		<updated>2026-08-17T10:43:33Z</updated>

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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:43, 17 August 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P68&quot; href=&quot;/wiki/Property:P68&quot;&gt;Canonical URI&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;&lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://id.who.int/icd/entity/1394279590&quot;&gt;https://id.who.int/icd/entity/1394279590&lt;/a&gt;&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Property / &lt;a title=&quot;Property:P68&quot; href=&quot;/wiki/Property:P68&quot;&gt;Canonical URI&lt;/a&gt;: &lt;a rel=&quot;nofollow&quot; class=&quot;external free&quot; href=&quot;https://id.who.int/icd/entity/1394279590&quot;&gt;https://id.who.int/icd/entity/1394279590&lt;/a&gt; / rank&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;span&gt;Normal rank&lt;/span&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Determinaradmin</name></author>
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		<updated>2026-08-17T10:43:32Z</updated>

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