{"entities":{"Q96378":{"pageid":86771,"ns":120,"title":"Item:Q96378","lastrevid":543650,"modified":"2026-08-16T12:20:58Z","type":"item","id":"Q96378","labels":{"mul":{"language":"mul","value":"ID_848611604"},"pt-br":{"language":"pt-br","value":"Amiloidose sist\u00eamica prim\u00e1ria afetando pele e/ou cavidade oral"},"en":{"language":"en","value":"Primary systemic amyloidosis affecting skin or oral cavity"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A amiloidose sist\u00eamica prim\u00e1ria, devido \u00e0 produ\u00e7\u00e3o anormal de fragmentos da cadeia leve de imunoglobulina causado pela discrasia das c\u00e9lulas plasm\u00e1ticas ou mieloma m\u00faltiplo, pode estar presente na pele. Os achados mais comuns s\u00e3o hemorragias petequiais espont\u00e2neas, p\u00farpura e hematomas. Essa hemorragia tem predile\u00e7\u00e3o pela pele com infiltra\u00e7\u00e3o amiloide clinicamente aparente: desenvolvem-se p\u00e1pulas e placas lisas, brilhantes, cerosas e transl\u00facidas, principalmente nas p\u00e1lpebras, no pesco\u00e7o e nas \u00e1reas que correspondem a locais de flex\u00e2o. Macroglossia ocorre em 10 por cento dos casos."},"en":{"language":"en","value":"Primary systemic amyloid, due to abnormal secretion of immunoglobulin light chain fragments as a result of plasma cell dyscrasia or multiple myeloma, may present in the skin. The commonest findings are spontaneous petechial haemorrhages, purpura and bruising. Such haemorrhage has a predilection for skin with clinically apparent amyloid infiltration: smooth, shiny, waxy, translucent papules and plaques develop, particularly on the eyelids, the neck and in flexural areas. Macroglossia occurs in 10 per cent of cases."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"5c3ab243717f63dc3d39e027c13d59de7e030858","datavalue":{"value":"https://id.who.int/icd/entity/848611604","type":"string"},"datatype":"url"},"type":"statement","id":"Q96378$0257F028-4B86-4D51-B09F-B77191A11B7C","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"a36f6a481c46396d0583e246391b51db84fd57cb","datavalue":{"value":"CID11:ID_848611604","type":"string"},"datatype":"string"},"type":"statement","id":"Q96378$FB3A678B-8C0A-4531-82D7-7910F0332B4A","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"08bed5c3bcc1fd4ab4e16b9d7651c45a60cb6db2","datavalue":{"value":"dki-india-ID_848611604","type":"string"},"datatype":"string"},"type":"statement","id":"Q96378$7A3B35D8-212C-4B5A-9076-8260424060D9","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q96378$62B195F6-2D94-42A5-81F3-E97AF17D331E","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q96378$B1FF9E59-C1CB-4249-AF1B-DE9B431E7F02","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q96378$21BD5160-95AF-4FED-BCCA-D2FF683BFC07","rank":"normal"}]},"sitelinks":{}}}}