{"entities":{"Q93404":{"pageid":83797,"ns":120,"title":"Item:Q93404","lastrevid":522142,"modified":"2026-08-16T08:30:34Z","type":"item","id":"Q93404","labels":{"mul":{"language":"mul","value":"ID_853926582"},"pt-br":{"language":"pt-br","value":"Forma sintom\u00e1tica da distrofia muscular de Becker em mulheres portadoras"},"en":{"language":"en","value":"Symptomatic form of Becker muscular dystrophy in female carriers"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A distrofia muscular de Becker (DMB) em mulheres portadoras \u00e9 caracterizada por graus vari\u00e1veis de fraqueza muscular devido \u00e0 miopatia esquel\u00e9tica progressiva, \u00e0s vezes associada a cardiomiopatia dilatada ou dilata\u00e7\u00e3o do ventr\u00edculo esquerdo. A preval\u00eancia \u00e9 desconhecida: apenas uma pequena porcentagem de mulheres portadoras foi identificada para manifestar essas doen\u00e7as (19% das mulheres portadoras de fam\u00edlias com DMB). Portadoras sintom\u00e1ticas do sexo feminino geralmente aparecem mais tarde na vida. Mulheres com caracter\u00edsticas cl\u00ednicas de DMB s\u00e3o geralmente portadoras de rearranjos do cromossomo X, apresentam inativa\u00e7\u00e3o anormal n\u00e3o aleat\u00f3ria do X ou t\u00eam s\u00edndrome de Turner (aus\u00eancia completa ou parcial de um cromossomo X). O progn\u00f3stico para portadoras sintom\u00e1ticas do sexo feminino \u00e9 vari\u00e1vel, mas o curso da doen\u00e7a tende a ser mais brando em mulheres do que em homens e a progress\u00e3o \u00e9 lenta."},"en":{"language":"en","value":"Becker muscular dystrophy (BMD) in females carriers are characterised by variable degrees of muscle weakness due to progressive skeletal myopathy, sometimes associated with dilated cardiomyopathy or left ventricle dilation. Prevalence is unknown: Only a small percentage of female carriers have been reported to manifest these diseases (19% of female carriers from families with BMD). Symptomatic female carriers usually present later in life. Females with clinical features of BMD are usually carriers of X-chromosome rearrangements, display skewed X-inactivation or have Turner syndrome (complete or partial absence of an X chromosome). The prognosis for symptomatic female carriers is variable, but the disease course tends to be milder in females than in males and progression is slow."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"a886d687d5c47b82b7babe2d1996477022326090","datavalue":{"value":"https://id.who.int/icd/entity/853926582","type":"string"},"datatype":"url"},"type":"statement","id":"Q93404$65ED3BA6-1870-47B5-B8C2-5A1A74C3059E","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"3c982d457c937026d444c31583b41292e7f04240","datavalue":{"value":"CID11:ID_853926582","type":"string"},"datatype":"string"},"type":"statement","id":"Q93404$DC9C45C4-DFC9-46D7-8A7B-C574B66AD140","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"d05549e277b8083a110512b36ad00184b1e8e8e7","datavalue":{"value":"dki-india-ID_853926582","type":"string"},"datatype":"string"},"type":"statement","id":"Q93404$A1F2C2C5-3239-4A4F-9D37-8276031D9D80","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q93404$7B94220E-094E-4531-89A2-BA5866B0B617","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q93404$DFB8536B-2EF7-4AEF-ABA2-BA647AA38045","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q93404$2103A718-6DB2-4EA8-83AB-4F0A9731A2F9","rank":"normal"}]},"sitelinks":{}}}}