{"entities":{"Q91564":{"pageid":81957,"ns":120,"title":"Item:Q91564","lastrevid":509307,"modified":"2026-08-15T18:35:32Z","type":"item","id":"Q91564","labels":{"mul":{"language":"mul","value":"ID_1305248013"},"pt-br":{"language":"pt-br","value":"Esferocitose heredit\u00e1ria"},"en":{"language":"en","value":"Hereditary spherocytosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Anemia hemol\u00edtica resultante de anormalidades na prote\u00edna de membrana dos gl\u00f3bulos vermelhos e \u00e9 causada por uma muta\u00e7\u00e3o geneticamente herdada levando a anemia hemol\u00edtica n\u00e3o imune mediada. Esta doen\u00e7a \u00e9 caracterizada pela produ\u00e7\u00e3o de gl\u00f3bulos vermelhos que tem a forma de esfera (esferocitose) em vez do formato do disco bic\u00f4ncavo normal. Esta diferen\u00e7a no formato tornam os gl\u00f3bulos vermelhos mais propensos a se romper. Esta doen\u00e7a pode se manifestar com palidez, icter\u00edcia, aumento do ba\u00e7o, fadiga e falta de ar. A confirma\u00e7\u00e3o \u00e9 pela identifica\u00e7\u00e3o da muta\u00e7\u00e3o atrav\u00e9s de teste gen\u00e9tico"},"en":{"language":"en","value":"A haemolytic anaemia resulting from red blood cell membrane protein anomalies and is caused by a genetically inherited mutation leading to non-immune mediated haemolytic anaemia. This disease is characterised by production of red blood cells that are sphere-shaped (spherocytosis) rather than the normal biconcave disk shaped. This difference in shape makes the red blood cells more prone to rupture. This disease may present with pallor, jaundice, enlarged spleen, fatigue, or shortness of breath. Confirmation is by identification of mutation through genetic testing."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"d92598d1498134728f45f233deaefe8b41b2a2d3","datavalue":{"value":"https://id.who.int/icd/entity/1305248013","type":"string"},"datatype":"url"},"type":"statement","id":"Q91564$14D3B37C-9364-4DD6-971D-E9B6C6644A6D","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"26ace268b969c89d4f92c474b9b48638f7ff1a2c","datavalue":{"value":"CID11:ID_1305248013","type":"string"},"datatype":"string"},"type":"statement","id":"Q91564$07BD6DA5-1E4F-4330-8109-856E8EC488C7","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"5504d1cd7fa3fbbeda561380cb9c38d1d1079d24","datavalue":{"value":"dki-india-ID_1305248013","type":"string"},"datatype":"string"},"type":"statement","id":"Q91564$4638C369-A37B-4FFC-92F3-142FF2F81E27","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q91564$E0D3DD36-70B3-432C-801D-6EE69A045762","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q91564$3CA7BEF4-B6A1-4C72-8EB1-D4982EC48E32","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q91564$DA69AB22-E97C-4071-A729-7D951E59AA77","rank":"normal"}]},"sitelinks":{}}}}