{"entities":{"Q89269":{"pageid":79654,"ns":120,"title":"Item:Q89269","lastrevid":492647,"modified":"2026-08-15T15:53:00Z","type":"item","id":"Q89269","labels":{"mul":{"language":"mul","value":"ID_256411659"},"pt-br":{"language":"pt-br","value":"Distonia devida \u00e0 s\u00edndrome de Leigh"},"en":{"language":"en","value":"Dystonia due to Leigh syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"\u00c9 uma condi\u00e7\u00e3o que ocorre entre 2 e 18 meses de idade, caracterizada por concentra\u00e7\u00f5es diminu\u00eddas de serotonina e catecolaminas. Os sintomas podem incluir: hipersaliva\u00e7\u00e3o, instabilidade de temperatura, pupilas puntiformes, ptose, crises oculog\u00edricas, hipocinesia, coreia distal, hipotonia troncular, dificuldades de degluti\u00e7\u00e3o, sonol\u00eancia e irritabilidade. Diagn\u00f3stico \u00e9 estabelecido pela descoberta de baixas concentra\u00e7\u00f5es de \u00e1cido homovan\u00edlico e 3-metoxi-4-hidroxifenilglicol no l\u00edquido espinhal e por testes gen\u00e9ticos."},"en":{"language":"en","value":"This is a condition presenting between 2-18 month sof age, characterized by decreased concentrations of serotonin and catecholamines. Symptoms may include: hypersalivation, temperature instability, pinpoint pupils, ptosis, oculogyric crises, hypokinesis, distal chorea, truncal hypotonia, swallowing difficulties, drowsiness and irritability. Diagnois is is established by finding low spinal fluid concentrations of homovanilic acid and 3-methoxy-4-hydroxy-phenylglycol and genetic testing."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"28cf244f5ede6402c327f135a16beef30dabe6d9","datavalue":{"value":"https://id.who.int/icd/entity/256411659","type":"string"},"datatype":"url"},"type":"statement","id":"Q89269$F8C28349-E281-4A6F-8ABF-92DF1B6EB6E3","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"0e9eafa0a25fdd9f4a9ff8127c86618062d8d383","datavalue":{"value":"CID11:ID_256411659","type":"string"},"datatype":"string"},"type":"statement","id":"Q89269$5A2CB737-512E-4DF1-A43C-ABDE0FA739D7","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"bfbd8d014712522aeda0e898eb78cbdb63ed1f9d","datavalue":{"value":"dki-india-ID_256411659","type":"string"},"datatype":"string"},"type":"statement","id":"Q89269$1373285D-1BE9-4345-A1C2-C1D346403701","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q89269$86A9E40E-E4F5-4F9D-A18C-2F381C218923","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q89269$07C829D5-3B2D-4D78-9FC3-9DC24E500E62","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q89269$868DC6F8-3B3F-4D47-940A-A5A6DE444B37","rank":"normal"}]},"sitelinks":{}}}}