{"entities":{"Q86922":{"pageid":77307,"ns":120,"title":"Item:Q86922","lastrevid":475579,"modified":"2026-08-15T12:29:39Z","type":"item","id":"Q86922","labels":{"mul":{"language":"mul","value":"ID_2134326880"},"pt-br":{"language":"pt-br","value":"Esclerose lateral amiotr\u00f3fica com dem\u00eancia frontotemporal"},"en":{"language":"en","value":"Amyotrophic lateral sclerosis with frontotemporal dementia"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Comprometimento cognitivo e mudan\u00e7as de comportamento refletindo particularmente uma disfun\u00e7\u00e3o de fun\u00e7\u00f5es do lobo frontal, como planejamento, fun\u00e7\u00f5es executivas e execu\u00e7\u00e3o de tarefas sequenciais complexas, ocorrem em uma propor\u00e7\u00e3o de pacientes com ELA. Existe um continuum, variando de mudan\u00e7as leves a franca dem\u00eancia frontotemporal (DFT). Exames de neuroimagem podem demonstrar atrofia, hipoperfus\u00e3o e hipometabolismo dos lobos frontal e temporal. Pacientes com expans\u00f5es C9ORF72 podem apresentar DFT, ELA ou s\u00edndromes de sobreposi\u00e7\u00e3o."},"en":{"language":"en","value":"Cognitive impairment and behaviour changes particularly reflecting dysfunction of frontal lobe functions, such as planning, executive functions, and performing complex sequential tasks, occur in a proportion of ALS patients. There is a continuum, ranging from mild changes to frank frontotemporal dementia (FTD). Neuroimaging may demonstrate atrophy, hypoperfusion, and hypometabolism of frontal and temporal lobes. Patients with C9ORF72 expansions may present with FTD, ALS or overlap syndromes."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"477784221e0362151ee1d55ca83b35425e8b3ec0","datavalue":{"value":"https://id.who.int/icd/entity/2134326880","type":"string"},"datatype":"url"},"type":"statement","id":"Q86922$9B1C7204-56AC-47AC-BDA7-6526EAA71358","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f6d7acd11dd64838f192096f60e8e81762fb709c","datavalue":{"value":"CID11:ID_2134326880","type":"string"},"datatype":"string"},"type":"statement","id":"Q86922$13D32A68-0EBA-4D5F-B758-7123D3618C01","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"9e6cc80c66689f800aa0d9f039ea2628a0a36db6","datavalue":{"value":"dki-india-ID_2134326880","type":"string"},"datatype":"string"},"type":"statement","id":"Q86922$45BA6961-A818-4388-92DD-2E5BA1C079D8","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q86922$10ED6678-C16B-4146-9607-7997312271BD","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q86922$E35477B0-C1D8-48B7-BBBD-564680C1D222","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q86922$44723751-BD08-42EF-94AF-26A6F5343F38","rank":"normal"}]},"sitelinks":{}}}}