{"entities":{"Q86205":{"pageid":76590,"ns":120,"title":"Item:Q86205","lastrevid":470359,"modified":"2026-08-15T11:34:22Z","type":"item","id":"Q86205","labels":{"mul":{"language":"mul","value":"ID_1663592623"},"pt-br":{"language":"pt-br","value":"Hipotireoidismo cong\u00eanito transit\u00f3rio por muta\u00e7\u00f5es heterozig\u00f3ticas de THOX2"},"en":{"language":"en","value":"Transient congenital hypothyroidism due to heterozygous mutations of THOX2"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Defeitos no gene tireoide-oxidase 2 (THOX2) resultam na aus\u00eancia de H2O2, essencial para a s\u00edntese dos horm\u00f4nios tireoidianos. Entretanto, muta\u00e7\u00f5es heterozig\u00f3ticas neste gene provocam hipotireoidismo cong\u00eanito transit\u00f3rio."},"en":{"language":"en","value":"Defects in the thyroid oxidase 2 (THOX2) gene result in a lack of H2O2, which is a protein essential for thyroid hormone synthesis. Therefore, heterozygous mutations in this gene lead to transient congenital hypothyroidism."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"3ecb1c7535ab9ab9ea35e134005f9299b9c2e372","datavalue":{"value":"https://id.who.int/icd/entity/1663592623","type":"string"},"datatype":"url"},"type":"statement","id":"Q86205$8F05D903-3D05-4AC5-9A73-8D1BDBA56ECF","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f785bddd8242db75ba6293b038e81029828098b1","datavalue":{"value":"CID11:ID_1663592623","type":"string"},"datatype":"string"},"type":"statement","id":"Q86205$3786EC7C-F773-4EF9-A580-931DD89EF8BA","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"887e591edadc6d0ba6899f0cfca9a159d9edcf1a","datavalue":{"value":"dki-india-ID_1663592623","type":"string"},"datatype":"string"},"type":"statement","id":"Q86205$503ADE05-9EC5-491C-B04C-45B2117E20E2","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q86205$B09F0BA4-06FC-4FBE-8FFD-61F3C0A93E8E","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q86205$CD646BC3-06FB-4D43-9CCD-5A23057C65B0","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q86205$873F9E04-6F9A-4AD5-9C4F-682303BBA374","rank":"normal"}]},"sitelinks":{}}}}