{"entities":{"Q84141":{"pageid":74526,"ns":120,"title":"Item:Q84141","lastrevid":455335,"modified":"2026-08-15T09:30:20Z","type":"item","id":"Q84141","labels":{"mul":{"language":"mul","value":"ID_936930510"},"pt-br":{"language":"pt-br","value":"Opsocl\u00f4nus-miocl\u00f4nus"},"en":{"language":"en","value":"Opsoclonus-myoclonus"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Opsocl\u00f4nus-miocl\u00f4nus (OM) \u00e9 um transtorno autoimune dos movimentos oculares caracterizado por opsocl\u00f4nus (movimentos oculares r\u00e1pidos [sac\u00e1dicos] involunt\u00e1rios e imprevis\u00edveis sem intervalos intersac\u00e1dicos), miocl\u00f4nus (breves contra\u00e7\u00f5es musculares involunt\u00e1rias). Ataxia est\u00e1 frequentemente presente e, enquanto a RNM costuma ser normal, o l\u00edquor pode ser inflamat\u00f3rio. OM pode ser paraneopl\u00e1sica, p\u00f3s infecciosa ou autoimune idiop\u00e1tica. OM paraneopl\u00e1sica em crian\u00e7as se associa a neuroblastoma, enquanto em adultos os c\u00e2nceres de mama e de pequenas c\u00e9lulas do pulm\u00e3o s\u00e3o os mais comuns. Muitos n\u00e3o apresentam um autoanticorpo neural concomitante, mas uma exce\u00e7\u00e3o \u00e9 o anticorpo anti-neuronal tipo 2 [ANNA-2 ou anti-Ri] que est\u00e1 associado aos c\u00e2nceres de mama, pulm\u00e3o e ginecol\u00f3gicos."},"en":{"language":"en","value":"Opsoclonus-myoclonus (OM) is an autoimmune disorder of eye movements characterised by opsoclonus (involuntary unpredictable rapid eye movements [saccades] without inter-saccadic intervals), myoclonus (brief involuntary twitches). Ataxia is often present and while MRI is usually normal, spinal fluid may be inflammatory. OM may be paraneoplastic, post-infectious or idiopathic autoimmune. Paraneoplastic OM in children associates with neuroblastoma, while in adults breast and small-cell-lung cancers are most common. Most do not have an accompanying neural autoantibody, but an exception is the anti-neuronal nuclear antibody type 2 [ANNA-2 or anti-Ri] which is associated with breast, lung and gynaecological cancers."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"c10fb655bde1bf7f8b5f5a002b7d2089d5d695ae","datavalue":{"value":"https://id.who.int/icd/entity/936930510","type":"string"},"datatype":"url"},"type":"statement","id":"Q84141$98FE5E54-C7A7-4AD2-BA52-42377E45FFC7","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f3aa4665a85e977cddf00babb60bcb5884bda971","datavalue":{"value":"CID11:ID_936930510","type":"string"},"datatype":"string"},"type":"statement","id":"Q84141$3082BE96-C480-481F-A679-6B624E249C3C","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"3fd7ef093d33be48808f3702b67f99b6e4fbf0a6","datavalue":{"value":"dki-india-ID_936930510","type":"string"},"datatype":"string"},"type":"statement","id":"Q84141$DC1FE8DF-21A5-4432-B7F7-099F063AC8CF","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84141$905133C5-FF28-4B8B-B55C-C1370B54A95F","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84141$0EC821B1-6678-42F1-BF66-8947E1DB582B","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84141$99CE4A78-F413-45F5-B0E4-DF35F91F0E85","rank":"normal"}]},"sitelinks":{}}}}