{"entities":{"Q68908":{"pageid":59290,"ns":120,"title":"Item:Q68908","lastrevid":345349,"modified":"2026-08-14T16:59:54Z","type":"item","id":"Q68908","labels":{"mul":{"language":"mul","value":"ID_887449084"},"pt-br":{"language":"pt-br","value":"Fibrose cong\u00eanita dos m\u00fasculos extraoculares"},"en":{"language":"en","value":"Congenital fibrosis of extraocular muscles"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Fibrose cong\u00eanita dos m\u00fasculos extraoculares (CFEOM) se refere a pelo menos sete s\u00edndromes estrab\u00edsmicas definidas: CFEOM1A, CFEOM1B, CFEOM2, CFEOM3A, CFEOM3B, CFEOM3C e s\u00edndrome de Tukel, caracterizadas por oftalmoplegia cong\u00eanita n\u00e3o progressiva com ou sem ptose (p\u00e1lpebra ca\u00edda). Em geral, os indiv\u00edduos afetados t\u00eam limita\u00e7\u00f5es importantes do olhar vertical (usualmente do olhar para cima) e limita\u00e7\u00e3o vari\u00e1vel do olhar horizontal. Indiv\u00edduos com CFEOM frequentemente compensam a oftalmoplegia mantendo posi\u00e7\u00f5es de cabe\u00e7a anormais quando em repouso e movimentam a cabe\u00e7a mais que os olhos para acompanhar objetos. Indiv\u00edduos com CFEOM3A tamb\u00e9m podem ter incapacidade intelectual, incapacidade de socializa\u00e7\u00e3o, fraqueza facial e/ou uma neuropatia perif\u00e9rica axonal progressiva (uma forma da doen\u00e7a de Charcot-Marie-Tooth). Indiv\u00edduos com s\u00edndrome de Tukel tamb\u00e9m t\u00eam oligodactilia p\u00f3s-axial ou oligosindactilia nas m\u00e3os."},"en":{"language":"en","value":"Congenital fibrosis of the extraocular muscles (CFEOM) refers to at least seven genetically defined strabismus syndromes: CFEOM1A, CFEOM1B, CFEOM2, CFEOM3A, CFEOM3B, CFEOM3C, and Tukel syndrome, characterised by congenital non-progressive ophthalmoplegia with or without ptosis (droopy eyelids). In general, affected individuals have severe limitation of vertical gaze (usually upgaze) and variable limitation of horizontal gaze. Individuals with CFEOM frequently compensate for the ophthalmoplegia by maintaining abnormal head positions at rest and by moving their heads rather than their eyes to track objects. Individuals with CFEOM3A may also have intellectual disability, social disability, facial weakness, and/or a progressive axonal peripheral neuropathy (a form of Charcot-Marie-Tooth disease). Individuals with Tukel syndrome also have postaxial oligodactyly or oligosyndactyly of the hands."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"142a21dcfaa9c6c0d2ace786f28eba8bc86811f2","datavalue":{"value":"https://id.who.int/icd/entity/887449084","type":"string"},"datatype":"url"},"type":"statement","id":"Q68908$783C4EF7-50E4-4FA5-8B12-8FF5517EBDC9","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"0c68fb8aefb7e5a6acdc79e17170ebbc985e835c","datavalue":{"value":"CID11:ID_887449084","type":"string"},"datatype":"string"},"type":"statement","id":"Q68908$3F0358DA-45F0-4E73-8079-4EEB3E9FD550","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"ee5e637cf6d60ec585f9c7976d002fb4134fb56a","datavalue":{"value":"dki-india-ID_887449084","type":"string"},"datatype":"string"},"type":"statement","id":"Q68908$ECB7A0C3-5358-483F-ACD2-B1A0306B545F","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q68908$6252F519-18BB-481F-BE65-7FB18A98ACFC","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q68908$AE70E221-0FA2-4A20-B969-0EC96DFD76F4","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q68908$1C429C50-E882-4AEE-A4E8-466A50B161A1","rank":"normal"}]},"sitelinks":{}}}}