{"entities":{"Q68131":{"pageid":58509,"ns":120,"title":"Item:Q68131","lastrevid":339809,"modified":"2026-08-14T15:59:36Z","type":"item","id":"Q68131","labels":{"mul":{"language":"mul","value":"ID_1993570575"},"pt-br":{"language":"pt-br","value":"S\u00edndrome de Fechtner"},"en":{"language":"en","value":"Fechtner syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"S\u00edndrome de Fechtner \u00e9 uma das s\u00edndromes MYH9 (um grupo que inclui quatro formas cl\u00ednicas com manifesta\u00e7\u00f5es semelhantes resultantes de muta\u00e7\u00f5es no gene MYH9: anomalia de May-Hegglin e s\u00edndromes de Sebastian e Epstein) que s\u00e3o caracterizadas por uma macrotrombocitopenia que geralmente \u00e9 grave mas paradoxalmente resulta em poucos ou nenhum sintoma. A macrotrombocitopenia \u00e9 definida pela presen\u00e7a de plaquetas gigantes, com di\u00e2metro igual ou superior ao di\u00e2metro de uma hem\u00e1cia. A s\u00edndrome de Fechtner associa de forma inconstante comprometimento renal (glomerulonefrite intersticial), surdez neurossensorial (especialmente na faixa de alta frequ\u00eancia) e catarata (potencialmente bilateral)."},"en":{"language":"en","value":"Fechtner syndrome is one of the MYH9 syndromes (a group that includes four clinical forms with similar manifestations resulting from mutations in the MYH9 gene: May-Hegglin anomaly and Sebastian and Epstein syndromes) which are characterised by a macrothrombocytopenia that is usually severe but paradoxically results in few if any symptoms. Macrothrombocytopenia is defined by the presence of giant platelets, with a diameter equal or superior to the diameter of a red cell. Fechtner syndrome inconstantly associates renal involvement (interstitial glomerulonephritis), sensorineural deafness (especially in the high frequency range), and cataract (potentially bilateral)."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"3e1990c9976499570cf4df28594834e51d3bb1d6","datavalue":{"value":"https://id.who.int/icd/entity/1993570575","type":"string"},"datatype":"url"},"type":"statement","id":"Q68131$D734CCD2-49EA-4CAB-A226-117FA3AFEDC9","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"2302119ccaacead97cf61f5cb4ec1decb085a4c3","datavalue":{"value":"CID11:ID_1993570575","type":"string"},"datatype":"string"},"type":"statement","id":"Q68131$A62FB504-E508-4DB3-AD97-1EB59BD2D63C","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"13643ae34cb57d761f14710491b9ecae197f04cf","datavalue":{"value":"dki-india-ID_1993570575","type":"string"},"datatype":"string"},"type":"statement","id":"Q68131$D0087D3C-9146-46D8-9A59-2D824EFEAFF4","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q68131$88FD74BE-2623-4734-9202-75916E722BA1","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q68131$CAFB047A-E4A0-489B-A351-EEB45D433B60","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q68131$575B7AB0-C68D-42C8-9988-066F01AE3437","rank":"normal"}]},"sitelinks":{}}}}