{"entities":{"Q67742":{"pageid":58120,"ns":120,"title":"Item:Q67742","lastrevid":337033,"modified":"2026-08-14T15:34:40Z","type":"item","id":"Q67742","labels":{"mul":{"language":"mul","value":"ID_848083807"},"pt-br":{"language":"pt-br","value":"Mucosulfatidose"},"en":{"language":"en","value":"Mucosulfatidosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A defici\u00eancia m\u00faltipla de sulfatases ou doen\u00e7a de Austin \u00e9 uma doen\u00e7a de dep\u00f3sito lisoss\u00f4mico extremamente rara, caracterizada por uma defici\u00eancia de todas as sulfatases, sejam lisoss\u00f4micas ou n\u00e3o. Clinicamente, a doen\u00e7a combina uma quimera \u200b\u200bde sinais cl\u00ednicos com intensidades vari\u00e1veis destas doen\u00e7as - leucodistrofia metacrom\u00e1tica (defici\u00eancia de arilsulfatase A), mucopolissacaridoses (tipos II, IIIA, IIID e VI s\u00e3o devidos a defici\u00eancias de sulfatase) e ictiose ligada ao X (defici\u00eancia de esteroide-sulfatase)."},"en":{"language":"en","value":"Multiple sulfatase deficiency (MSD) or Austin's disease is an extremely rare lysosomal storage disease characterised by a deficiency of all sulfatases whether lysosomal or not. Clinically, the disease combines variable proportions of clinical signs of metachromatic leukodystrophy (arylsulfatase A deficiency), mucopolysaccharidoses (types II, IIIA, IIID and VI are due to sulfatase deficiencies) and X-linked ichthyosis (steroid-sulfatase deficiency)."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"d01d55bd5b771f79b253698107a1f07d02c8e0f3","datavalue":{"value":"https://id.who.int/icd/entity/848083807","type":"string"},"datatype":"url"},"type":"statement","id":"Q67742$72779E5B-D868-4467-82AE-EF8759964BEC","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"612da0b1afd63d91680990ebf1195ca412360445","datavalue":{"value":"CID11:ID_848083807","type":"string"},"datatype":"string"},"type":"statement","id":"Q67742$CEC5E30D-0047-4164-B715-B0E2FA600684","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"aedc9b3cf60943de866be79e4b6a3de70c08a7c2","datavalue":{"value":"dki-india-ID_848083807","type":"string"},"datatype":"string"},"type":"statement","id":"Q67742$7DB42059-6B9B-492A-BC60-574D12A06611","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q67742$C336ACC1-B5C7-4F79-907A-1D51CDA9F004","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q67742$3B9CF636-EA0B-4ACD-9AD5-72B714D1CB33","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q67742$6EC228E7-DE69-4975-9DEC-B08CC6A2FB5C","rank":"normal"}]},"sitelinks":{}}}}