{"entities":{"Q46035":{"pageid":36406,"ns":120,"title":"Item:Q46035","lastrevid":177484,"modified":"2026-08-13T14:21:41Z","type":"item","id":"Q46035","labels":{"mul":{"language":"mul","value":"LA06.1"},"pt-br":{"language":"pt-br","value":"Hipoplasia ou agenesia dos hemisf\u00e9rios cerebelares"},"en":{"language":"en","value":"Hypoplasia or agenesis of cerebellar hemispheres"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Hipoplasia cerebelar corresponde ao subdesenvolvimento de estruturas cerebelares, que pode envolver o vermis e/ou os hemisf\u00e9rios cerebelares de agenesia parcial a total. Tem sido descrita no contexto de v\u00e1rias entidades cl\u00ednicas: anomalias cromoss\u00f4micas, exposi\u00e7\u00e3o intrauterina a toxinas e agentes infecciosos, dist\u00farbios metab\u00f3licos (dist\u00farbios de glicosila\u00e7\u00e3o e defici\u00eancias de CoQ10) e uma grande variedade de doen\u00e7as neurol\u00f3gicas gen\u00e9ticas raras. Pode estar restrita ao cerebelo ou afetar outras estruturas do SNC: o mesenc\u00e9falo (s\u00edndromes dentais molares), ponte e medula (hipoplasia ponto-cerebelar), c\u00f3rtex cerebral (s\u00edndromes de hipoplasia cerebelar com lissencefalia)."},"en":{"language":"en","value":"Cerebellar hypoplasia corresponds to underdevelopment of cerebellar structures that can involve the vermis and/or the cerebellar hemispheres from partial to total agenesis. It has been described in the context of various clinical entities: chromosomal anomalies, in utero exposure to toxins and infectious agents, metabolic disorders (disorders of glycosylation and CoQ10 deficiencies), and a wide variety of rare genetic neurological diseases. It can be confined to the cerebellum, or affect other CNS structures: the midbrain (molar tooth syndromes), pons and medulla (ponto-cerebellar hypoplasia), cerebral cortex (lissencephaly cerebellar hypoplasia syndromes)."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"ed8818a7c45bd486ce8c5a8753d5c20b367bdded","datavalue":{"value":"https://id.who.int/icd/entity/2029581479","type":"string"},"datatype":"url"},"type":"statement","id":"Q46035$95CB896E-CC74-4930-AA8E-7E5CB6EBF1EF","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"de4fd9a2de5bef2e4349ed5cf71d28e3eb39a01f","datavalue":{"value":"CID11:LA06.1","type":"string"},"datatype":"string"},"type":"statement","id":"Q46035$247DBDAB-2E25-405F-B0B0-ECF6A46EAD1F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"2631b132c2e742a3387e4168b745127a26f5184c","datavalue":{"value":"dki-india-LA06.1","type":"string"},"datatype":"string"},"type":"statement","id":"Q46035$AAECB1FA-DAB3-444F-A3D8-ED3A534335CD","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q46035$F7C9BD57-5614-4682-980E-93EAFBCF8550","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q46035$7CCAD369-9B38-4AA1-85E3-86D871097CC1","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q46035$846A1D5C-0067-478C-A7FE-59CE9EE2D6AE","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"447b6c31ed553f52a8fd65b850ae4c88cd664677","datavalue":{"value":{"entity-type":"item","numeric-id":21804,"id":"Q21804"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q46035$0F048CD6-4891-4BEE-A63A-94BC5704E398","rank":"normal"}]},"sitelinks":{}}}}