{"entities":{"Q41052":{"pageid":31420,"ns":120,"title":"Item:Q41052","lastrevid":134942,"modified":"2026-08-13T07:06:29Z","type":"item","id":"Q41052","labels":{"mul":{"language":"mul","value":"8B60"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a do neur\u00f4nio motor"},"en":{"language":"en","value":"Motor neuron disease"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Doen\u00e7a do neur\u00f4nio motor \u00e9 um transtorno neurodegenerativo de etiologia indeterminada, caracterizado por degenera\u00e7\u00e3o de neur\u00f4nios motores superiores (c\u00e9lulas corticais de Betz e trato corticoespinal) ou neur\u00f4nios motores inferiores (cornos ventrais da medula espinal e n\u00facleos motores dos nervos cranianos) ou ambos. Caracter\u00edsticas de envolvimento dos neur\u00f4nios motores inferiores (NMI) s\u00e3o atrofia, fraqueza, fascicula\u00e7\u00f5es, hipotonia, diminui\u00e7\u00e3o ou aus\u00eancia de reflexos tendinosos profundos. Caracter\u00edsticas de envolvimento dos neur\u00f4nios motores superiores (NMS) s\u00e3o espasticidade, reflexos tendinosos profundos exacerbados e respostas plantares extensoras. Dependendo da localiza\u00e7\u00e3o de in\u00edcio e da presen\u00e7a de caracter\u00edsticas de NMI ou NMS ou ambos, a DNM t\u00eam padr\u00f5es e distribui\u00e7\u00f5es vari\u00e1veis de sinais e sintomas."},"en":{"language":"en","value":"Motor neuron disease is a neurodegenerative disorder of undetermined etiology, characterised by degeneration of upper motor neurons (cortical Betz cells and corticospinal tract) or lower motor neurons (ventral horns of spinal cord and cranial nerve motor nuclei) or both. Features of involvement of lower motor neurons (LMN) are atrophy, weakness, fasciculations, hypotonia, decreased or absent deep tendon reflexes. Features of involvement of upper motor neurons (UMN) are spasticity, exaggerated deep tendon reflexes, and extensor plantar responses. Depending on the site of onset and the presence of UMN or LMN features or both, MND has varying patterns and distributions of signs and symptoms."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"7b902fcfe429a108a349eb60db8a6468dbd092b3","datavalue":{"value":"https://id.who.int/icd/entity/661720689","type":"string"},"datatype":"url"},"type":"statement","id":"Q41052$77A382EC-8C31-49C5-B198-D76DC526F9C2","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"2f916cd14265408baf347f258660fa3008eec1ac","datavalue":{"value":"CID11:8B60","type":"string"},"datatype":"string"},"type":"statement","id":"Q41052$AB128D70-28C4-48C0-9B12-6649639622A6","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"271b24591c765e6c76fae9386bedf61db2602a81","datavalue":{"value":"dki-india-8B60","type":"string"},"datatype":"string"},"type":"statement","id":"Q41052$AAAF226C-6689-443F-AE45-6F3CE75E7A0F","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q41052$BA9ED381-036B-4DDE-8978-9FA1444C5997","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q41052$7432FFA0-F946-4D32-9CA5-EDDA8F4B0016","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q41052$9CBD61BF-C9E5-417A-A507-580451797586","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"ea31a01f219e449243632e6aea5d14e92c40b2c6","datavalue":{"value":{"entity-type":"item","numeric-id":16832,"id":"Q16832"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q41052$601C304D-5129-4F07-A11B-29A4422BBAED","rank":"normal"}]},"sitelinks":{}}}}