{"entities":{"Q38479":{"pageid":28845,"ns":120,"title":"Item:Q38479","lastrevid":112984,"modified":"2026-08-13T03:33:28Z","type":"item","id":"Q38479","labels":{"mul":{"language":"mul","value":"1F57.2"},"pt-br":{"language":"pt-br","value":"Toxoplasmose pulmonar devida a Toxoplasma gondii"},"en":{"language":"en","value":"Pulmonary toxoplasmosis due to Toxoplasma gondii"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Em pacientes imunodeficientes, a toxoplasmose ocorre mais frequentemente em pessoas com defeitos na imunidade mediada por c\u00e9lulas T, como aqueles que recebem corticosteroides, terapias antifator de necrose tumoral (TNF) ou drogas citot\u00f3xicas, e aqueles com doen\u00e7as hematol\u00f3gicas malignas, transplantes de \u00f3rg\u00e3os ou s\u00edndrome de imunodefici\u00eancia adquirida (SIDA). _x000D_ A toxoplasmose pulmonar no paciente imunodeficiente pode aparecer na forma de pneumonite intersticial, pneumonite necrotizante, consolida\u00e7\u00e3o, derrame pleural ou empiema, ou todos eles. _x000D_ Pacientes com SIDA e pneumonia por Toxoplasma apresentam tosse, dispneia e febre. Como a toxoplasmose geralmente \u00e9 observada apenas na infec\u00e7\u00e3o avan\u00e7ada por HIV com contagens de CD4 abaixo de 100, a maioria dos pacientes com SIDA que desenvolvem pneumonia por toxoplasma j\u00e1 teve infec\u00e7\u00f5es oportunistas anteriores associadas ao HIV. Em pacientes transplantados de \u00f3rg\u00e3os s\u00f3lidos, isso ocorre mais comumente devido ao transplante de um pulm\u00e3o ou cora\u00e7\u00e3o de um doador soropositivo para toxoplasma para um receptor soronegativo, resultando em doen\u00e7a pulmonar prim\u00e1ria. Em pacientes transplantados de medula \u00f3ssea, a toxoplasmose pulmonar ocorre em 0,28% a 0,45% dos pacientes. Ao contr\u00e1rio dos pacientes com transplante de \u00f3rg\u00e3os s\u00f3lidos, a maioria desses pacientes apresenta reativa\u00e7\u00e3o, n\u00e3o doen\u00e7a prim\u00e1ria."},"en":{"language":"en","value":"In immunodeficient patients, toxoplasmosis most often occurs in persons with defects in T cell\u2013mediated immunity such as those receiving corticosteroids, anti\u2013tumour necrosis factor (TNF) therapies, or cytotoxic drugs and those with hematologic malignancies, organ transplants, or acquired immunodeficiency syndrome (AIDS). Pulmonary toxoplasmosis in the immunodeficient patient may appear in the form of interstitial pneumonitis, necrotizing pneumonitis, consolidation, pleural effusion, or empyema, or all of these. AIDS patients with Toxoplasma pneumonia present with cough, dyspnoea, and fever. As toxoplasmosis is generally seen only in advanced HIV infection with CD4 counts below 100, the majority of AIDS patients who develop toxoplasma pneumonia already have had previous HIV-associated opportunistic infections. In solid organ transplant patients, this is most commonly due to transplantation of a toxoplasma-seropositive lung or heart into a seronegative recipient, resulting in primary pulmonary disease. In bone marrow transplant patients, pulmonary toxoplasmosis occurs in 0.28% to 0.45% of patients. Unlike solid organ transplant patients, most of these patients have reactivation, not primary disease."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"e7af2b019a03a5f922479c4cc2de203b85c07855","datavalue":{"value":"https://id.who.int/icd/entity/1165131409","type":"string"},"datatype":"url"},"type":"statement","id":"Q38479$F4AE5EDA-C20C-45BE-B02E-52F9E5372795","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f1a6615da160f1f13eb772c761e1a25ce4718040","datavalue":{"value":"CID11:1F57.2","type":"string"},"datatype":"string"},"type":"statement","id":"Q38479$1C38D255-F4FC-4D26-ADBF-01E46209A6D4","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"436218825b24dada116038a6b1f8a1652f4a85ba","datavalue":{"value":"dki-india-1F57.2","type":"string"},"datatype":"string"},"type":"statement","id":"Q38479$58CA5866-656B-4E20-BD15-87B8B1AD188A","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q38479$B22C9CEB-A03B-41FD-8E09-6E214E1E5ACD","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q38479$B0B0BB81-DE7C-4FCB-86DD-E1F511580B5C","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q38479$047EEACC-ECDB-4896-B939-882B459026CE","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"e2529a75fca49b93c4b23ffc30276444f4018d68","datavalue":{"value":{"entity-type":"item","numeric-id":12554,"id":"Q12554"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q38479$6005DCDC-0BDC-4D31-9859-D37AFF469FC5","rank":"normal"}]},"sitelinks":{}}}}