{"entities":{"Q105935":{"pageid":96331,"ns":120,"title":"Item:Q105935","lastrevid":612672,"modified":"2026-08-17T12:34:05Z","type":"item","id":"Q105935","labels":{"mul":{"language":"mul","value":"ID_1994802431"},"pt-br":{"language":"pt-br","value":"Hiperaldosteronismo familiar tipo 1"},"en":{"language":"en","value":"Familial hyperaldosteronism type 1"}},"descriptions":{"pt-br":{"language":"pt-br","value":"O hiperaldosteronismo familiar tipo I, tamb\u00e9m chamado de aldosteronismo supress\u00edvel por dexametasona, \u00e9 uma doen\u00e7a heredit\u00e1ria rara devido \u00e0 express\u00e3o ect\u00f3pica da aldosterona sintase na zona fascicular da gl\u00e2ndula adrenal e marcada com hipertens\u00e3o grave precoce (frequentemente ocorrendo antes dos 20 anos), sinais biol\u00f3gicos de aldosteronismo prim\u00e1rio de intensidade vari\u00e1vel e um n\u00edvel elevado anormal de 18-oxo e 18-hidroxicortisol."},"en":{"language":"en","value":"Type I familial aldosteronism, also called dexamethasone suppressible aldosteronism, is a rare inherited disorder due to the ectopic expression of the aldosterone synthase in the fascicular zone of the adrenal gland and marked with early severe hypertension (often occurring before the age of 20), biological signs of primary aldosteronism of variable intensity, and an abnormal elevated level of 18-oxo- and 18-hydroxycortisol."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"abf1f5b9036b4fe3c05f299639a6e0e90b562e70","datavalue":{"value":"https://id.who.int/icd/entity/1994802431","type":"string"},"datatype":"url"},"type":"statement","id":"Q105935$8C58712B-48E1-473C-9717-E8B6DC59BAE0","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"a9dd0b58206ffabb89aba08ce0dc5f1824c6768d","datavalue":{"value":"CID11:ID_1994802431","type":"string"},"datatype":"string"},"type":"statement","id":"Q105935$78A07B58-C33A-4212-9345-8E5D9F01ECA8","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"257a7ec9f1d8c5e8a3e24a376a5e69c271d4ad48","datavalue":{"value":"dki-india-ID_1994802431","type":"string"},"datatype":"string"},"type":"statement","id":"Q105935$9697A417-5613-4302-A1B2-EF4EC92AD1D7","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q105935$49DF0295-9005-4825-B1B1-D45AEF7E185E","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q105935$AE0B3AC1-29B7-4F4A-960C-B88430F94C87","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q105935$079D4C47-2314-4BBF-8BBD-21C977FA1559","rank":"normal"}]},"sitelinks":{}}}}