{"entities":{"Q104859":{"pageid":95257,"ns":120,"title":"Item:Q104859","lastrevid":605021,"modified":"2026-08-17T10:43:13Z","type":"item","id":"Q104859","labels":{"mul":{"language":"mul","value":"ID_1679749810"},"pt-br":{"language":"pt-br","value":"Dismorfismo digitotalar"},"en":{"language":"en","value":"Digitotalar dysmorphism"}},"descriptions":{"pt-br":{"language":"pt-br","value":"O dismorfismo digitotalar ou artrogripose distal tipo 1 \u00e9 uma anomalia cong\u00eanita autoss\u00f4mica dominante caracterizada por contraturas das regi\u00f5es distais das m\u00e3os e p\u00e9s sem anomalias adicionais. \u00c9 o tipo mais comum de artrogripose distal. A expressividade \u00e9 vari\u00e1vel e os pacientes podem apresentar camptodactilia, polegares em cruz sem extens\u00e3o, dedos em relevo, desvio ulnar dos dedos, p\u00e9 torto, t\u00e1lus vertical. O envolvimento facial geralmente est\u00e1 ausente. As m\u00e3os est\u00e3o mais frequentemente envolvidas do que os p\u00e9s. V\u00e1rios genes que codificam prote\u00ednas no sarc\u00f4mero foram implicados."},"en":{"language":"en","value":"Digitotalar dysmorphism or distal arthrogryposis type 1 is an autosomal dominant congenital anomaly characterised by contractures of the distal regions of the hands and feet with no additional anomalies. It is the most common type of distal arthrogryposis. Expressivity is variable and patients may present camptodactyly, clasped thumbs without extension, overriding fingers, ulnar deviation of the fingers, clubfoot, vertical talus. Facial involvement is typically absent. The hands are most frequently involved than the feet. Multiple genes encoding proteins in the sarcomere have been implicated."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"f5c5a1bd00a3616278ecfd4effcc29cb12f7c54c","datavalue":{"value":"https://id.who.int/icd/entity/1679749810","type":"string"},"datatype":"url"},"type":"statement","id":"Q104859$5C50CD2F-ACF9-46CE-A6C3-00F3C04351B2","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"a403dd09d73933d1bad81c66c09aed552b23781b","datavalue":{"value":"CID11:ID_1679749810","type":"string"},"datatype":"string"},"type":"statement","id":"Q104859$7638E0D2-EBA7-4B4D-8DBC-BC9AB6D93183","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"ee368bff8eb9e2c33d76ed88ac8f05a3c9ad4cad","datavalue":{"value":"dki-india-ID_1679749810","type":"string"},"datatype":"string"},"type":"statement","id":"Q104859$68B5C5D4-F818-4CA6-B5E8-F57D0697ECDD","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q104859$0AF58164-3076-4B1B-A3F6-30B0EE2B53E2","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q104859$66B2A3AE-2F6C-428B-A661-38F92A6D6EAF","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q104859$F1D1A142-1EF4-4BED-9A29-6EC571224D85","rank":"normal"}]},"sitelinks":{}}}}