{"entities":{"Q101690":{"pageid":92083,"ns":120,"title":"Item:Q101690","lastrevid":582124,"modified":"2026-08-16T18:32:01Z","type":"item","id":"Q101690","labels":{"mul":{"language":"mul","value":"ID_110429919"},"pt-br":{"language":"pt-br","value":"S\u00edndrome hipereosinof\u00edlica"},"en":{"language":"en","value":"Hypereosinophilic syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"S\u00edndrome hipereosinof\u00edlica (SHE) constitui um grupo raro e heterog\u00eaneo de transtornos, definido como eosinofilia sangu\u00ednea persistente e acentuada (maior que 1,5 x 10 [9a pot\u00eancia]/L por mais de seis meses consecutivos, associada a evid\u00eancias de danos a \u00f3rg\u00e3os induzidos por eosin\u00f3filos, quando outras causas de hipereosinofilia, como transtornos al\u00e9rgicos, parasit\u00e1rios e malignos, foram exclu\u00eddos._x000D_ _x000D_ Informa\u00e7\u00f5es adicionais: As apresenta\u00e7\u00f5es cl\u00ednicas variam, desde envolvimento cut\u00e2neo benigno at\u00e9 manifesta\u00e7\u00f5es graves, como endomiocardiofibrose e tromboembolismo. Os subtipos incluem a associa\u00e7\u00e3o com a s\u00edndrome de Churg-Strauss (granulomatose eosinof\u00edlica com poliangiite), neoplasias mieloides, variante linfoc\u00edtica de c\u00e9lulas T e endocardite de Loeffler, assim como a idiop\u00e1tica."},"en":{"language":"en","value":"Hypereosinophilic syndrome (HES) constitute a rare and heterogeneous group of disorders, defined as persistent and marked blood eosinophilia (greater than 1.5 x 10[9th power]/L for more than six consecutive months, associated with evidence of eosinophil-induced organ damage, where other causes of hypereosinophilia such as allergic, parasitic, and malignant disorders have been excluded. Additional information: Clinical presentations vary, from benign cutaneous involvement to severe manifestations such as endomyocardial fibrosis and thromboembolism. Subtypes include the association with Churg-Strauss syndrome (eosinophilic granulomatosis with polyangiitis), myeloid neoplasms, T cell lymphocytic variant and Loeffler's endocarditis, as well as idiopathic."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"4a0ae107f5fb0dfa5ddf74f06f1e06081eb50cc1","datavalue":{"value":"https://id.who.int/icd/entity/110429919","type":"string"},"datatype":"url"},"type":"statement","id":"Q101690$1AC101C3-EF64-4213-B369-E912631F5C23","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"979b3559ac906d3459e2f1c37fba7c947ba52a5e","datavalue":{"value":"CID11:ID_110429919","type":"string"},"datatype":"string"},"type":"statement","id":"Q101690$BB53BE5E-81E8-4BDF-9F60-E068DC138A78","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"2bfafce5b1aea27bdf5689631339a8c28c20e280","datavalue":{"value":"dki-india-ID_110429919","type":"string"},"datatype":"string"},"type":"statement","id":"Q101690$F2C0B246-17D6-40E6-8F90-93F9B0D9E95F","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q101690$5D604F14-1113-4A9A-95D6-8EE73A480CC1","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q101690$52065220-4BB7-4560-9D5C-D43360021A1A","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q101690$54555FF8-7ABE-485F-ABF7-642377DBCB7F","rank":"normal"}]},"sitelinks":{}}}}